Innovative Initiative to Detect and Prevent Genetic Disorders Nationwide
In a landmark step towards ensuring the health and well-being of future generations, the United Arab Emirates (UAE) will introduce mandatory premarital genetic testing for all Emirati couples starting January 2024. This pioneering initiative aligns with the national strategy to promote public health and prevent genetic disorders, the Ministry of Health and Prevention (MoHAP) announced on Wednesday.
A Nationwide Rollout for Genetic Health
Initially launched as a pilot program in Abu Dhabi in 2022, the genetic screening strategy has been meticulously designed to identify and address hereditary conditions. Following its resounding success in the capital, where more than 800 couples participated, the program will now extend to all Emirates.
Led by MoHAP in collaboration with Abu Dhabi’s Department of Health, the Dubai Health Authority, Emirates Health Services, and Dubai Health, the program also involves contributions from academic, medical, and technological partners. The Emirates Genome Council, which approved the scheme during recent UAE government annual meetings, has provided strategic directives for this initiative.
Comprehensive Genetic Screening
The program will screen for 570 genes linked to over 840 medical conditions, equipping couples with vital insights into their genetic compatibility. By identifying potential genetic mutations, the initiative aims to reduce the transmission of preventable hereditary conditions to future generations. Couples will have the opportunity to make informed family planning decisions, supported by early medical intervention when necessary.
Key Outcomes and Benefits
The Abu Dhabi trial phase, which became mandatory in October 2023, demonstrated significant impact. Data revealed that 86% of couples achieved genetic compatibility, while 14% required additional intervention based on their genetic results. Medical experts highlighted the initiative’s critical role in lowering the burden of hereditary diseases in the UAE.
“The Department of Health – Abu Dhabi has integrated genetic testing as a core element of its premarital screening program, aiming to reduce the incidence of inherited diseases in the Emirate,” said Dr. Ayman El-Hattab, a consultant in clinical genetics at Burjeel Medical City. “This expanded screening will significantly enhance public health outcomes by identifying a broader spectrum of genetic conditions.”
Addressing Genetic Disorders in the UAE
The program’s relevance is underscored by the high prevalence of genetic disorders within the Emirati population, partly due to the region’s history of consanguineous marriages. Dr. Fahed Al Marzooqi, Deputy Chief Operating Officer of M42, emphasized the initiative’s potential to transform healthcare outcomes.
“Understanding genetic risks allows healthcare providers to take proactive measures, improving patient outcomes and reducing the long-term burden of chronic diseases like cardiovascular disease and diabetes,” Dr. Al Marzooqi noted.
Building a Healthier Future
A key objective of the initiative is the creation of an integrated genetic database. This resource will empower healthcare providers to identify genetic diseases proactively and implement early interventions. The database also represents a crucial step towards advancing the UAE’s healthcare system through cutting-edge genomic research and technology.
The UAE’s comprehensive approach to genetic screening reinforces its commitment to protecting public health and ensuring the well-being of its citizens. By fostering informed decision-making among couples and reducing hereditary disease prevalence, this initiative marks a significant stride toward a healthier and more resilient future for Emirati families.